Information for Contributors

Neurotherapeutics (www.neurotherapeutics.org) is the official journal of the American Society for Experimental NeuroTherapeutics (ASENT). Each issue of this publication provides critical invited reviews of an important topic relating to the treatment of neurological disorders. Neurotherapeutics is published quarterly, in both print and full-text online versions. The journal includes critical literature reviews, examination of controversies, editorial commentaries and exploration of experimental, clinical, legislative, regulatory, societal and ethical issues that affect neurotherapeutics.

Each issue of this journal has a special Guest Editor. All review manuscripts will be solicited by the Guest Editor(s). Submission of a manuscript implies that the data have not been published previously and will not be submitted for publication elsewhere while the manuscript is under review.

Manuscript Preparation

Timeline: Because Neurotherapeutics volumes are topic specific, it is very important that authors adhere to the deadlines as communicated by the Guest Editor. Articles can be sent earlier than requested. But, late articles cannot be rolled into the next issue. If authors fail to meet the timeline, the article will not be published.

Electronic Submission: Neurotherapeutics requires electronic submission of manuscripts and illustrations.

Review process: With submission, authors should send the name and contact information, including email address, of three reviewers who would be well suited to comment on the paper.

General Format: All text should be double-spaced (including references, tables, and legends). Margins should be 1 inch wide and all pages should be numbered. The following sections must begin on separate pages: Title page, Abstract/Key words, References, Acknowledgments, Tables, and Figure legends. A 12-point serif font, preferably Times New Roman, is required. Each article should fall in the range of between 20 and 30 double-spaced pages in a word processing document including all figures, tables and references , unless otherwise instructed by the Guest Editor. If there are any subheadings of the article it should be clear by font size or style or numbering how they are formatted (major vs. minor vs. subminor, etc).

Cross-citation: It is important that each article cites a few of the other articles in the dedicated volume. This will produce flow among the articles and cohesiveness to the volume. The Guest Editor will provide the preliminary Table of Contents to each author at the time of their assignment.

The Title Page must include the full title; a running title (not to exceed 40 characters); the author's full name (first name, middle initial, surname); the affiliations of all authors and their institutions, departments or organizations (use the following symbols in this order: *, †, ‡, §, ¶, ||, #, **, ††, ‡‡, §§, ¶¶, || ||, ##). Also on this page, the corresponding author's address including telephone, fax numbers, and e-mail should be included at the bottom of this page.

The Abstract must be 250 words or less and should be unstructured. References should not be included in the abstract.

Key Words: Please include at the end of the Abstract 5 or 6 Key Words or phrases to support indexing and information retrieval.

Acknowledgments must appear immediately after the text and before references. All grant support should be included in this section.

References are numbered in the order of citation in the text and should appear in the text as superscripts after periods and commas but before semicolons and colons. The citation should be closely match to the name. Thus avoid “Smith et al. found that . . . . . .47” and instead use “Smith et al.47 found that…”. References must be double-spaced. The format of the actual reference is shown below. Note that the first six authors must be listed. If citations are included in tables or in figure legends, they must be numbered according to the position of the citation of the table or figure in the text. Only published papers and papers "in press" may be included in the references. Web based citations may be included in the reference list (see example below). Citations of "manuscripts in preparation," "unpublished observations," "submitted for publication,” and "personal communications" must appear parenthetically in the text. Written approval by the person(s) cited in personal communications must accompany the manuscript unless they are also an author of the manuscript submitted. For references that are papers presented at a conference, please provide page numbers and abstract numbers whenever they are available.

Format for references:

Book:
Iverson C, Flanagin A, Fontanorose PB. American Medical Association manual of style. Ed 9. Baltimore, MD: Williams & Wilkins, 1998.

Chapter in Edited Book:
Gutzmann H, Hadler D, Erzigkeit H. Long-term treatment of Alzheimer's disease with idebenone. In: Alzheimer's disease: biology, diagnosis and therapeutics (Iqbal K, Winbald B, Nishimura T, Takeda M, Wisniewski HM, eds), Vol 2, Ed 2, Ch 2, pp 687-705. UK: Wiley, 1997.

(For books, list city only if it is a major city or city and state otherwise).

Journal article with up to six authors:
Yakovlev AG, Knoblach SM, Fan L, Fox GB, Goodnight R, Faden AI. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J Neurosci 17:7415-7424, 1997.

Journal article with two authors:
Trump BF, Bulger RE. Studies of cellular injury in isolated flounder tubules. I. Correlation between morphology and function of control tubules and observations of autophagocytosis and mechanical cell damage. Lab Invest 16:453-482, 1967.

Journal article with more than six authors:
Hartmann A, Hunot S, Michel PP, Muriel MP, Vyas S, Faucheux BA, et al. Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci USA 97:2875-2880, 2000.

Web-based citation in advance of publication in print:
Starr PA, Rau GM, Davis V, Marks WJ, Ostrem JL, Simmons D, et al. Spontaneous pallidal neuronal activity in human dystonia: comparison with Parkinson's disease and normal macaque. J Neurophysiol (insert DOI number here), 9 February 2005

Web-based citation not appearing in print:
Bakshi R. Fatigue and multiple sclerosis: a review. Medscape Neurology and Neurosurgery . Available at: http://www.medscape.com/viewarticle/462361_4, Accessed November 11, 2003

Abbreviations must be defined in the text with first use, but not defined again thereafter. Abbreviations should not be used only once unless it seems necessary for clarity. Abbreviations and their definitions must be consistent throughout the text.

Figure Legends must be numbered with Arabic numerals in order of appearance in the text and should include a short title after the figure number. Where possible, symbols and patterns used to distinguish data must be defined in a key placed within the graphic rather than in the figure legend.

Tables must be numbered with Arabic numerals in order of appearance in the text. Table legends are prepared as footnotes to the table and are included with the table.

Figures: Permission to reproduce previously published figures must be obtained in writing by the author from the copyright holder and kept on file by the author. In the figure legend, provide the exact full name and location (city/state or city/foreign country) of the publisher. It should be made clear in the figure legend if the figure is being reproduced with permission or adapted with permission. Articles cannot be published unless figure permissions have been obtained. Only illustrations where color representation is essential to the scientific content should be submitted in color. Illustrations where color representation is nonessential to the scientific content should be submitted in black and white. If color reproduction is required, this should be clearly stated in the figure legend as a note to the publisher.

Instructions for preparation of figures are below.

Electronic Submission

Neurotherapeutics requires electronic submission of manuscripts and illustrations.

Manuscripts should be prepared in Microsoft Word with an identical version created as a PDF file. Manuscript files should contain the Title page, Abstract, Key words, Acknowledgments, References, Tables, and Figure legends.

Figures should be prepared in electronic format as individual TIFF or EPS files. Resolution should be 300 dpi for images and 1200 dpi for line art. Authors should see the Cadmus Digital Art web site (http://cjs.cadmus.com/da/index.asp) for further details.

Uploading of Manuscript and Figures: The manuscript and figures including first draft and revisions should be uploaded on the Neurotherapeutics web site. Specific instructions and links for this uploading will be emailed directly to the authors by the Guest Editor.

Reprints must be ordered in advance of publication. A form showing the cost of reprints, together with an order slip, is sent with the page proofs. Reprint orders from non-contributors must be directed to the Editorial Office.

Manuscripts published in Neurotherapeutics become the sole property of, with all rights in copyright reserved to, the American Society for Experimental Neurotherapeutics. A copyright assignment form is signed by the corresponding author on behalf of all authors. Authors of articles written as part of their official duties as employees of the U.S. Government are exempt from this requirement for assignment transfer of copyright. Any previously copyrighted material reproduced in the manuscript, including modified figures and tables, must be accompanied by written permission from the copyright holder.

Manuscripts and figures are not returned to authors.